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Downloads and loads a single epigenomic differential analysis (DA) result table for a specified tissue and ome from the public AWS release. Files are hosted on Amazon CloudFront and accessed via a static HTTPS URL.

This function is intended for internal use and is called by load_DA_from_AWS to populate tissue–ome combinations.

Usage

.load_single_ome_tissue_AWS(
  selected_ome,
  selected_tissue,
  data_category = "da",
  version = "1.2"
)

Arguments

selected_ome

character; epigenomic ome to load (e.g., "epigen-methylcap-seq" or "epigen-atac-seq").

selected_tissue

character; tissue identifier.

data_category

character; analysis category, default is "da" for differential analysis.

version

character; dataset version identifier appended to the file name

Value

A data.frame containing the differential analysis results for the specified tissue and ome. If no matching tissue–ome combination is found, the function returns NULL.

Details

The underlying files are part of the public AWS release of the human pre-suspension sedentary adult epigenomics analyses. File naming conventions vary slightly across epigenomic assays and are handled internally.

To accommodate large epigenomic result files, the global R connection timeout is temporarily increased within this function.

Author

Christopher Jin