Load Epigenomic Differential Analysis Results from AWS

Loads publicly released epigenomic differential analysis (DA) results for selected tissues and omes directly from an AWS-backed content delivery network (CDN). These datasets are hosted on Amazon CloudFront and are accessed via HTTPS without requiring authentication or AWS credentials. Only needed for epigenetic files because these are too large for the package.

This function iterates over the requested tissue–ome combinations and retrieves each corresponding DA table using .load_single_ome_tissue_AWS. The returned object mirrors the nested list structure used elsewhere in the package, with tissues at the top level and omes at the second level.

The AWS-hosted files correspond to the public release of the human pre-suspension sedentary adult epigenomics analyses.

Usage

load_DA_from_AWS(selected_tissues, selected_omes)

Arguments

selected_tissues: character vector; one or more tissues for which differential analysis results should be retrieved.
selected_omes: character vector; one or more epigenomic omes to load (e.g., "epigen-methylcap-seq", "epigen-atac-seq").

Value

A nested list of data.frame objects. The top-level names correspond to tissues, and the second-level names correspond to omes. Each entry contains a differential analysis table loaded from the AWS public release.

Details

Files are served via Amazon CloudFront and downloaded on demand at runtime. Connection timeouts are increased internally to accommodate large epigenomic result files.

Author

Christopher Jin

Examples

if (FALSE) { # \dontrun{
DA_epigen <- load_DA_from_AWS(
  selected_omes = c("epigen-methylcap-seq"),
  selected_tissues = c("muscle", "adipose")
)
} # }