Rat-to-human gene ortholog map

Mapping between various rat and human gene identifiers for orthologs as reported by RGD (2020-01-10).

Usage

RAT_TO_HUMAN_GENE

Format

A data frame with 21461 rows and 12 variables:

RAT_SYMBOL

character, official rat gene symbol

NAME

character, gene name

RAT_GENE_RGD_ID

integer, rat RGD gene ID

RAT_NCBI_GENE_ID

integer, rat NCBI/Entrez gene ID

RAT_ENSEMBL_ID

character, rat Ensembl gene ID

RAT_UNIPROT_ID

character, semicolon-separated list of rat UniProt gene IDs

RAT_OLD_SYMBOL

character, semicolon-separated list of rat deprecated or alias gene symbols

HUMAN_ORTHOLOG_SYMBOL

character, human official gene symbol

HUMAN_ORTHOLOG_RGD

character, human RGD gene ID

HUMAN_ORTHOLOG_NCBI_GENE_ID

character, human NCBI/Entrez gene ID

HUMAN_ORTHOLOG_ENSEMBL_ID

character, human Entrez gene ID

HUMAN_ORTHOLOG_SOURCE

character, human ortholog source

Source

<https://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_39/gencode.v39.metadata.EntrezGene.gz>
<https://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_39/gencode.v39.metadata.HGNC.gz>
<https://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_39/gencode.v39.chr_patch_hapl_scaff.basic.annotation.gtf.gz>
<https://download.rgd.mcw.edu/pub/data_release/RGD_ORTHOLOGS.txt> (2020-01-10)
<https://download.rgd.mcw.edu/data_release/RAT/GENES_RAT.txt> (2020-11-15)

Details

This map was compiled from several external sources. GENCODE metadata and annotation files were used to map between human Ensembl transcript IDs, Entrez IDs, GENCODE IDs, and Ensembl gene IDs (Frankish et al., 2021). RGD files were used to map between human and rat gene symbols as well as between various rat gene identifiers (Smith et al., 2020).

There is one row per unique combination of \code{RAT_SYMBOL}, \code{RAT_GENE_RGD_ID}, \code{RAT_NCBI_GENE_ID}, \code{RAT_ENSEMBL_ID},
\code{RAT_UNIPROT_ID}, \code{HUMAN_ORTHOLOG_SYMBOL}, \code{HUMAN_ORTHOLOG_RGD}, \code{HUMAN_ORTHOLOG_NCBI_GENE_ID}, and \code{HUMAN_ORTHOLOG_ENSEMBL_ID}, 
so some genes correspond to multiple rows in the table. For example, there are 24 rows corresponding to \code{RAT_SYMBOL == "Tnf"} 
because 3 \code{RAT_ENSEMBL_ID}s correspond to Tnf, and 8 \code{HUMAN_ORTHOLOG_ENSEMBL_ID}s correspond to TNF.