Statistical analysis results of the fiber cross-sectional area data by muscle and fiber type.

FIBER_AREA_STATS

Format

An object of class data.frame with 56 rows and 21 columns:

response

character; the measurement being tested. All "Mean Fiber Area".

age

factor; the age of the rat at the beginning of the training protocol. Levels: "6M" (Adult) and "18M" (Aged).

sex

factor; the sex of the rat with levels "Female" and "Male".

muscle

factor; the muscle that was sampled with levels "LG" (lateral gastrocnemius), "MG" (medial gastrocnemius), "PL" (plantaris), and "SOL" (soleus).

type

factor; the muscle fiber type with levels "I", "IIa", "IIx", and "IIb".

contrast

factor; the comparison between groups. All contrasts are ratios between the 8W and SED group means ("8W / SED").

estimate_type

character; interpretation of the value in the estimate column. All "ratio" (ratio between group means, as specified by contrast).

null

numeric; the value of the estimate under the null hypothesis.

estimate

numeric; ratio between the means of the groups as specified by contrast.

SE

numeric; the standard error of the estimate.

lower.CL

numeric; lower bound of the 95% confidence interval.

upper.CL

numeric; upper bound of the 95% confidence interval.

statistic_type

character; the type of statistical test. All "t" (Student's t-statistic).

statistic

numeric; the value of the test statistic.

df

numeric; the number of residual degrees of freedom.

p.value

numeric; the p-value associated with the statistical test.

p.adj

numeric; the Holm-adjusted p-value.

signif

logical; TRUE if p.adj < 0.05.

model_type

character; the statistical model used for testing. All "lme" (linear mixed effects model).

fixed

character; the fixed-effects component of the model formula. Describes the response variable (and any transformations) and all predictor variables that were included. Equivalent to formula.

random

character; the random component of the model formula. Specifies the random effects for mixed effects models. All "~1 | pid" (random intercept for each rat).

Examples

head(FIBER_AREA_STATS)
#>          response age    sex muscle type contrast estimate_type null  estimate
#> 1 Mean Fiber Area  6M Female     LG    I 8W / SED         ratio    1 0.9858807
#> 2 Mean Fiber Area  6M Female     LG  IIa 8W / SED         ratio    1 1.0077985
#> 3 Mean Fiber Area  6M Female     LG  IIx 8W / SED         ratio    1 1.0069759
#> 4 Mean Fiber Area  6M Female     LG  IIb 8W / SED         ratio    1 0.9865055
#> 5 Mean Fiber Area  6M Female     MG    I 8W / SED         ratio    1 1.0947372
#> 6 Mean Fiber Area  6M Female     MG  IIa 8W / SED         ratio    1 1.1627512
#>           SE  lower.CL upper.CL statistic_type  statistic df   p.value
#> 1 0.06716298 0.8590696 1.131411              t -0.2087328 40 0.8357162
#> 2 0.06865613 0.8781682 1.156564              t  0.1140301 40 0.9097843
#> 3 0.06860009 0.8774514 1.155620              t  0.1020439 40 0.9192317
#> 4 0.06720554 0.8596140 1.132128              t -0.1994340 40 0.8429336
#> 5 0.07457881 0.9539241 1.256336              t  1.3286536 40 0.1914926
#> 6 0.07921226 1.0131897 1.334390              t  2.2134207 40 0.0326355
#>        p.adj signif model_type
#> 1 1.00000000  FALSE        lme
#> 2 1.00000000  FALSE        lme
#> 3 1.00000000  FALSE        lme
#> 4 1.00000000  FALSE        lme
#> 5 0.19149264  FALSE        lme
#> 6 0.06527099  FALSE        lme
#>                                               fixed   random
#> 1 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid
#> 2 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid
#> 3 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid
#> 4 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid
#> 5 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid
#> 6 log(fiber_area) ~ age * sex * group * muscle_type ~1 | pid